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Comparison of referred pain from jaw muscles caused by mechanical and chemical stimulation (Aarhus)

 
Du kan muligvis deltage i dette forsøg hvis du:
  • Er rask.
  • Er mere end 18 år gammel.
  • Ikke tager medicin regelmæssigt.
  • English speaking

This study will beperformed as a randomized, double-blinded, controlled design. Participants willparticipate in 2 sessions at least 2 days apart. At both sessions, mechanicalsensitivity will be tested in the mid-portion of the masseter muscle with theuse of 4 different forces (before and after glutamate injection) and glutamate (either 1.0 M, 0.2 mL or0.25 M, 0.2mL) willbe injected into the mid-portion of the masseter muscle.

Inclusioncriteria:

  • Over18 years old.
  • No ongoing orofacial pain or any other reportedchronic pain in last 6 months.
  • Noserious systemic diseases, received radiotherapy or chemotherapy.
  • No psychogenic illness, such as depression.
  • No chronic intake medication of pain killers orhistory of use of any type of analgesics in the last 24 hours previous to theexperiment.

Compensation:

The participants will receive financial compensation of DDK 150,-/h (intotal, DDK 300,- for participating in the study), which is reported to the taxauthorities.

  • Please refer to the e-mail those who participationhope, will send the detailed information.

*About Glutamate

L-glutamic acid isclassified as a nonessential amino acid. L-glutamic acid may help nerve cells send and receiveinformation from other cells. L-glutamic acid is used as a component ofparenteral and enteral nutrition. L-glutamic acid has the greatest demand ofany single amino acid, exceeding 1.5 million tons per year on a global basis. L-glutamicacid is manufactured by fermentation from carbohydrate sources. Carbohydratesare used as the raw material; no materials of animal origin are used in themanufacturing process. (Reference from: Ajinomoto. co)




 
 
 
 
Godkendt af etisk komité med journalnummer: MJ-:000000
 


Gen Udagawa
Department of Dentistry and Oral Health Section of Orofacial Pain and Jaw Function Aarhus University
Vennelyst Boulevard 9
8000 Aarhus
Tlf: 87167400
genudagawa@odont.au.dk